Aurora B regulates chromosome segregation and cytokinesis and is the first protein to be implicated as a regulator of bipolar attachment of spindle ...
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Sep 27, 2022 · Increased Aurora B protein expression, which is common in cancers, is expected to increase Aurora B kinase activity, yielding elevated ...
Aurora kinase B is a protein that functions in the attachment of the mitotic spindle to the centromere. AURKB. Available structures.
Jun 12, 2012 · Aurora B is a mitotic checkpoint kinase that plays a pivotal role in the cell cycle, ensuring correct chromosome segregation and normal ...
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May 25, 2023 · An entropy switch controls the Aurora B autoactivation process through two distinct kinetic steps of phosphorylation.
Mar 13, 2020 · The Aurora B abscission checkpoint delays cytokinesis until resolution of DNA trapped in the cleavage furrow. This process involves PKCε ...
Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player in chromosome segregation. As part of a macromolecular complex ...
Apr 28, 2009 · Aurora kinase-A and -B are key regulators of the cell cycle and tumorigenesis. It has remained a mystery why these 2 Aurora kinases, ...
Aurora B kinase is the catalytic subunit of the Chromosomal Passenger Complex (CPC) which also includes regulatory proteins INCENP, Survivin and Borealin ( ...
Aug 27, 2012 · We present the structure of the human Aurora B kinase domain in complex with the C-terminal Aurora-binding region of human INCENP and the ...