Aurora B regulates chromosome segregation and cytokinesis and is the first protein to be implicated as a regulator of bipolar attachment of spindle ...
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Sep 27, 2022 · Increased Aurora B protein expression, which is common in cancers, is expected to increase Aurora B kinase activity, yielding elevated ...
Mar 19, 2013 · Aurora B (Aurkb) is one of the major protein kinases that ensures the proper execution and fidelity of mitosis. A member of the chromosomal ...
Aurora kinase B is a protein that functions in the attachment of the mitotic spindle to the centromere. AURKB. Available structures.
May 25, 2023 · An entropy switch controls the Aurora B autoactivation process through two distinct kinetic steps of phosphorylation.
Feb 4, 2021 · Aurora B kinase is aberrantly overexpressed in various tumors and shown to be a promising target for anti-cancer therapy.
Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player in chromosome segregation. As part of a macromolecular complex ...
Aurora B kinase is the catalytic subunit of the chromosomal passenger complex (CPC) which also includes regulatory proteins INCENP, Survivin, and Borealin (van ...
Aug 27, 2012 · We present the structure of the human Aurora B kinase domain in complex with the C-terminal Aurora-binding region of human INCENP and the ...
Aug 18, 2020 · Here, we identify six new phosphorylation sites in caspase-2 and show that a key mitotic kinase, Aurora B kinase (AURKB), phosphorylates caspase ...