Aurora B regulates chromosome segregation and cytokinesis and is the first protein to be implicated as a regulator of bipolar attachment of spindle ...
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Sep 27, 2022 · Increased Aurora B protein expression, which is common in cancers, is expected to increase Aurora B kinase activity, yielding elevated ...
Aurora kinase B is a protein that functions in the attachment of the mitotic spindle to the centromere. AURKB. Available structures.
Aurora B is a key actor of mitosis. Results: The BRAF/ERK axis regulates Aurora B. Vemurafenib-resistant melanoma cells are sensitive to Aurora B inhibition.
May 25, 2023 · An entropy switch controls the Aurora B autoactivation process through two distinct kinetic steps of phosphorylation.
Mar 13, 2020 · The Aurora B abscission checkpoint delays cytokinesis until resolution of DNA trapped in the cleavage furrow. This process involves PKCε ...
Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player in chromosome segregation. As part of a macromolecular complex ...
Aurora B kinase is the catalytic subunit of the Chromosomal Passenger Complex (CPC) which also includes regulatory proteins INCENP, Survivin and Borealin ( ...
Aurora B antibody for analysis of mitosis and meiosis by Immunofluorescence (IF), ICC and Western Blot.
BI-1266 is a potent and selective Aurora B inhibitor that inhibits cell proliferation and could be used as tool compound testing biological hypotheses.